Dr. habil. Tadeusz Kuliński
profesor instytutu
Dr. Natalia Szóstak
adiunkt
Dr. Nicoletta Makowska
adiunkt
Dr. Dorota Magner
asystent
Dr. Joanna Sarzyńska
starszy specjalista biolog
Dr. Aneta Sawikowska
starszy specjalista biolog
Dr. habil. Małgorzata Oczko-Wojciechowska
area expert
Philips A, Stolarek I, Handschuh L, Nowis K, Juras A, Trzciński D, Nowaczewska W, Wrzesińska A, Potempa J, Figlerowicz M. Analysis of oral microbiome from fossil human remains revealed the significant differences in virulence factors of modern and ancient Tannerella forsythia. BMC Genomics. 2020 Jun 15;21(1):402. doi: 10.1186/s12864-020-06810-9.
Makowska N, Philips A, Dabert M, Nowis K, Trzebny A, Koczura R, Mokracka J. Metagenomic analysis of β-lactamase and carbapenemase genes in the wastewater resistome. Water Res. 2020 Mar 1;170:115277. doi: 10.1016/j.watres.2019.115277. Epub 2019 Nov 7.
Czubak K, Taylor K, Piasecka A, Sobczak K, Kozlowska K, Philips A, Sedehizadeh S, Brook JD, Wojciechowska M, Kozlowski P. Global Increase in Circular RNA Levels in Myotonic Dystrophy. Front Genet. 2019 Jul 18;10:649. doi: 10.3389/fgene.2019.00649. eCollection 2019.
Stolarek I, Juras A, Handschuh L, Marcinkowska-Swojak M, Philips A, Zenczak M, Dębski A, Kóčka-Krenz H, Piontek J, Kozlowski P, Figlerowicz M. A mosaic genetic structure of the human population living in the South Baltic region during the Iron Age. Sci Rep. 2018 Feb 6;8(1):2455. doi: 10.1038/s41598-018-20705-6.
Jackowiak P, Hojka-Osinska A, Philips A, Zmienko A, Budzko L, Maillard P, Budkowska A, Figlerowicz M. Small RNA fragments derived from multiple RNA classes - the missing element of multi-omics characteristics of the hepatitis C virus cell culture model. BMC Genomics. 2017 Jun 30;18(1):502. doi: 10.1186/s12864-017-3891-3.
Philips A, Stolarek I, Kuczkowska B, Juras A, Handschuh L, Piontek J, Kozlowski P, Figlerowicz M. Comprehensive analysis of microorganisms accompanying human archaeological remains. Gigascience. 2017 Jul 1;6(7):1-13. doi: 10.1093/gigascience/gix044.
NGS:
Analysis of differential gene expression
Analysis of differential expression of transcripts (alternative splicing)
Assembly of transcriptomes ab initio (based on genome) and de novo (without genome sequence) and their annotation
Identification of new genes and splicing forms
Analysis of non-coding RNAs (miRNA, piRNA, circRNA ect.)
Identification of miRNA target sequences
SNP identification
CNV identification
Analysis of WGS, exons (Exome-Seq) and selected genes (targeted sequencing)
De novo assembly of genomes and their annotation
Metagenomics analyses
Structure modeling:
Modeling 3D structures of proteins and nucleic acids; introducing modifications,
Thermodynamic analyzes
Docking of ligands to proteins / RNA
RNA structure prediction from NGS data
Other:
Data mining
Statistical analyses
Analysis of biological data in Python and Bioconductor (R language)
Computers with high computing power
Computing cluster
NGS
WGS
RNA-seq
DE
Metagenomics
Transcriptomics
SNP
CNV
PCA
Docking
Structure Modeling
Strona zrobiona w kreatorze stron internetowych WebWave
Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl
Sekretariat Dyrektora, tel: 61 852 89 19