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Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl
Sekretariat Dyrektora, tel: 61 852 89 19
Dr. Łukasz Przybył
Head of Laboratory
lprzybyl@ibch.poznan.pl
Phone:. 61 8291857
Laboratory uses the infrastructure of the Animal Facility (Individually Ventilated Cages, autoclaves, operating tables, vaporizers for inhalational anesthesia)
surgical tools
Zadora J, Singh M, Herse F, Przybyl L, Haase N, Golic M, Yung HW, Huppertz B, Cartwright JE, Whitley G, Johnsen GM, Levi G, Isbruch A, Schulz H, Luft FC, Müller DN, Staff AC, Hurst LD, Dechend R, Izsvák Z. Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker. Circulation. 2017
Ibrahim T*, Przybyl L*, Harmon AC, Amaral LM, Faulkner JL, Cornelius DC, Cunningham MW, Hünig T, Herse F, Wallukat G, Dechend R, LaMarca B. Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy. Am J Reprod Immunol. 2017
Laboratory of Mammalian Model Organisms offers complex assistance in performing animal experiments. We offer scientific and technical support in animal research in regards to:
planning a budget for grant proposals
experimental design of timeline and groups according to the 3R’s rule and ARRIVE guidelines
approvals from Local Ethical Committee, Ministry of Environment or Main Veterinary Inspectorate
organization of experimental animal transport
acquisition of required documentation to enter and use Animal Facility
training in basic techniques used in animal research
maintenance of mouse colonies (transgenic or wild-type)
acquisition of embryonic material on specific developmental stage
injections: intramuscular, intraperitoneal, subcutaneous, intracranial
microsurgery
transcardial perfusion, organ weighing and sampling, blood withdrawal
management of mouse colony database
keeping experimental records
basic behavioral, phenotyping observations and postoperative care
digitalization of data acquired during animal experiment, drawing graphs and basic statistical analysis
deep mouse immunophenotyping using flow cytometry
organization of Animal Facility infrastructure to be included into animal experiments, e.g. computed tomography, in vivo imaging system PhotonImager, motoric and cognitive functions assessment using PhenoMaster ActiMot2 and IntelliCage systems respectively, hematological and biochemical tests from mouse blood, metabolic cages
Ewa Karpińska MSc, BEng.
biologist
Dorota Wronka BEng..
biologist
Krystian Bocian
biologist