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Cooperation

Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl

Sekretariat Dyrektora, tel: 61 852 89 19

Address

Laboratory of Mammalian Model Organisms

Dr. Łukasz Przybył

Head of Laboratory
lprzybyl@ibch.poznan.pl
Phone:. 61 8291857

  • in vivo,
  • mouse,
  • model organisms,
  • breeding,
  • phenotype,
  • surgery,
  • immunity

Keywords

  • Laboratory uses the infrastructure of the Animal Facility (Individually Ventilated Cages, autoclaves, operating tables, vaporizers for inhalational anesthesia)

  • surgical tools

Equipment

  • Zadora J, Singh M, Herse F, Przybyl L, Haase N, Golic M, Yung HW, Huppertz B, Cartwright JE, Whitley G, Johnsen GM, Levi G, Isbruch A, Schulz H, Luft FC, Müller DN, Staff AC, Hurst LD, Dechend R, Izsvák Z. Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker. Circulation. 2017 

  • Ibrahim T*, Przybyl L*, Harmon AC, Amaral LM, Faulkner JL, Cornelius DC, Cunningham MW, Hünig T, Herse F, Wallukat G, Dechend R, LaMarca B. Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy. Am J Reprod Immunol. 2017 

Selected publications

Research activity

Laboratory of Mammalian Model Organisms offers complex assistance in performing animal experiments. We offer scientific and technical support in animal research in regards to:

  • planning a budget for grant proposals

  • experimental design of timeline and groups according to the 3R’s rule and ARRIVE guidelines

  • approvals from Local Ethical Committee, Ministry of Environment or Main Veterinary Inspectorate

  • organization of experimental animal transport

  • acquisition of required documentation to enter and use Animal Facility

  • training in basic techniques used in animal research

  • maintenance of mouse colonies (transgenic or wild-type)

  • acquisition of embryonic material on specific developmental stage

  • injections: intramuscular, intraperitoneal, subcutaneous, intracranial

  • microsurgery

  • transcardial perfusion, organ weighing and sampling, blood withdrawal

  • management of mouse colony database

  • keeping experimental records

  • basic behavioral, phenotyping observations and postoperative care

  • digitalization of data acquired during animal experiment, drawing graphs and basic statistical analysis

  • deep mouse immunophenotyping using flow cytometry

  • organization of Animal Facility infrastructure to be included into animal experiments, e.g. computed tomography, in vivo imaging system PhotonImager, motoric and cognitive functions assessment using PhenoMaster ActiMot2 and IntelliCage systems respectively, hematological and biochemical tests from mouse blood, metabolic cages

Offer

Research Projects

Ewa Karpińska MSc, BEng.

biologist

Researchers:

Dorota Wronka BEng..

biologist

Krystian Bocian

biologist