Dr. inż. Małgorzata Marcinkowska-Swojak
adiunkt
Dr. Patrick Perrigue
adiunkt
Dr. Natalia Koralewska
adiunkt
Dr. Lucyna Budźko
adiunkt
Dr. habil. Paulina Jackowiak
adiunkt
Philips A, Nowis K, Stelmaszczuk M, Jackowiak P, Podkowiński J, Handschuh L, Figlerowicz M. Expression landscape of circRNAs in Arabidopsis thaliana seedlings and adult tissues. Frontiers in Plant Science 2020, in press
Philips A , Nowis K, Stelmaszczuk M , Podkowiński J, Handschuh L , Jackowiak P, Figlerowicz M. Arabidopsis thaliana cbp80, c2h2, and flk knockout mutants accumulate increased amounts of circular RNAs. Cells 2020; 9(9):E1937
Perrigue PM, Rakoczy M, Pawlicka KP, Belter A, Giel-Pietraszuk M, Naskręt-Barciszewska M, Barciszewski J, Figlerowicz M. Cancer stem cell-inducing media activates senescence reprogramming in fibroblasts. Cancers 2020; 12(7): 1745
Zmienko A, Marszalek-Zenczak M, Pawel Wojciechowski P, Samelak-Czajka A, Luczak M, Kozlowski P, Karlowski WM, Figlerowicz M.
AthCNV: A Map of DNA Copy Number Variations in the Arabidopsis Genome. Plant Cell 2020; 32(6): 1797–1819
Stolarek I, Handschuh L, Juras A, Nowaczewska W, Kóčka-Krenz H, Michalowski A, Piontek J, Kozlowski P, Figlerowicz M. Goth migration induced changes in the matrilineal genetic structure of the central-east European population. Sci Rep. 2019; 9(1):6737
Jackowiak P, Lis A, Luczak M, Stolarek I, Figlerowicz M. Functional characterization of RNA fragments using high-throughput interactome screening. J Proteomics. 2019;193:173-183
Stolarek I, Juras A, Handschuh L, Marcinkowska-Swojak M, Philips A, Zenczak M, Dębski A, Kóčka-Krenz H, Piontek J, Kozlowski P, Figlerowicz M. A mosaic genetic structure of the human population living in the South Baltic region during the Iron Age. Sci Rep. 2018;8(1):2455
Handschuh L, Wojciechowski P, Kaźmierczak M, Marcinkowska-Swojak M, Łuczak M, Lewandowski K, Komarnicki M, Blazewicz J, Figlerowicz M, Kozlowski P. NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome. J Transl Med. 2018, 16(1):232
Handschuh L, Kaźmierczak M, Milewski MC, Góralski M, Łuczak M, Wojtaszewska M, Uszczyńska-Ratajczak B, Lewandowski K, Komarnicki M, Figlerowicz M. Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR. Int J Oncol. 2018, 52:656-678
Handschuh L. Not Only Mutations Matter: Molecular Picture of Acute Myeloid Leukemia Emerging from Transcriptome Studies. Journal of Oncology, 2019, 7239206
Jackowiak P, Hojka-Osinska A, Gasiorek K, Stelmaszczuk M, Gudanis D, Gdaniec Z, Figlerowicz M. Effects of G-quadruplex topology on translational inhibition by tRNA fragments in mammalian and plant systems in vitro. Int J Biochem Cell Biol. 2017;92:148-154
Jackowiak P, Hojka-Osinska A, Philips A, Zmienko A, Budzko L, Maillard P, Budkowska A, Figlerowicz M. Small RNA fragments derived from multiple RNA classes - the missing element of multi-omics characteristics of the hepatitis C virus cell culture model. BMC Genomics. 2017;18(1):502
Budzko L, Jackowiak P, Kamel K, Sarzynska J, Bujnicki JM, Figlerowicz M. Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro. Sci Rep. 2017;7(1):3873
Philips A, Stolarek I, Kuczkowska B, Juras A, Handschuh L, Piontek J, Kozlowski P, Figlerowicz M. Comprehensive analysis of microorganisms accompanying human archaeological remains. Gigascience. 2017;6(7):1-13
Samelak-Czajka A, Marszalek-Zenczak M, Marcinkowska-Swojak M, Kozlowski P, Figlerowicz M, Zmienko A. MLPA-Based Analysis of Copy Number Variation in Plant Populations. Front Plant Sci. 2017;8:222
Zmienko A, Samelak-Czajka A, Kozlowski P, Szymanska M, Figlerowicz M. Arabidopsis thaliana population analysis reveals high plasticity of the genomic region spanning MSH2, AT3G18530 and AT3G18535 genes and provides evidence for NAHR-driven recurrent CNV events occurring in this location. BMC Genomics. 2016;17(1):893
Marcinkowska-Swojak M, Handschuh L, Wojciechowski P, Goralski M, Tomaszewski K, Kazmierczak M, Lewandowski K, Komarnicki M, Blazewicz J, Figlerowicz M, Kozlowski P. Simultaneous detection of mutations and copy number variation of NPM1 in the acute myeloid leukemia using multiplex ligation-dependent probe amplification. Mutat Res. 2016;786:14-26
Perrigue PM, Najbauer J, Barciszewski J. The histone demethylase JMJD3 at the intersection of cellular senescence and cancer. BBA Rev on Cancer 2016;1865(2):237-244
Perrigue PM, Najbauer J, Jozwiak AA, Barciszewski J, Aboody KS, Barish ME. Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo. Pathobiol Aging Age Relat Dis. 2015;5:30052
Kurzynska-Kokorniak A, Koralewska N, Pokornowska M, Urbanowicz A, Tworak A, Mickiewicz A, Figlerowicz M. The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities. Nucleic Acids Res. 2015;43(9):4365-80
Zmienko A, Samelak A, Kozlowski P, Figlerowicz M. Copy number polymorphism in plant genomes. Theor Appl Genet. 2014;127(1):1-18
Kurzynska-Kokorniak A1, Koralewska N, Tyczewska A, Twardowski T, Figlerowicz M. A New Short Oligonucleotide-Based Strategy for the Precursor-Specific Regulation of microRNA Processing by Dicer. PLoS One. 2013 Oct 29;8(10):e77703
Jackowiak P, Nowacka M, Strozycki PM, Figlerowicz M. RNA degradome – its biogenesis and functions. Nucleic Acids Res. 2011;39(17):7361-70
RPWP.02.01.01-30-0001/20 REGIONAL COVID-HUB. WROP 2014-2020 2.1 Development of electronic public services Sub-measure 2.1.1 Development of electronic public services
2019/35/B/NZ2/02658 Comprehensive analysis of the Schmidtea mediterranea transcriptome – identification of non-coding RNAs involved in cell lineage development during regeneration. NCN OPUS 18
LIDER/30/0111/L-9/17NCBR/2018 Mapping of cytosine modifications in nucleic acids using AID/APOBEC enzymes. NCBR LIDER 9
POIR.04.01.02-00-0025/17-00 Polish Microbiome Map. SG OP Measure 4.1. Research and development Sub-measure 4.1.2 Regional research agendas
POIR.04.02.00-30-A004/16 European Centre of Bioinformatics and Genomics – Polish Genome Project. SG OP Measure 4.2. Development of modern research infrastructure in the science sector
820431 LifeTime – Revolutionizing Healthcare by Tracking and Understanding Human Cells During Disease. European Commission
2016/21/D/NZ3/00641 Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer. NCN SONATA 11
2014/13/B/NZ2/03837 Elucidation of the mechanisms that induce copy number polymorphism of large genome fragments and of the relations between this phenomenon and metabolic gene cluster formation and evolution in plants. NCN OPUS 7
2014/12/W/NZ2/00466 Dynasty and population of the Piast State in view of the integrated historical, anthropological and genomic studies. NCN SYMFONIA 2
Polish Infrastructure of Screening Platform for Biological Chemistry Project (POL-OPENSCREEN), a part of the European Infrastructure of Open Screening Platforms for Chemical Biology European Research Infrastructure Consortium(EU-OPENSCREEN ERIC). Polish Ministry of Science and Higher Education
Prof. Marek Figlerowicz
Head of Department
marek.figlerowicz@ibch.poznan.pl
ext.1103
Karolina Hoffa-Sobiech MSc Eng.
biolog
Marcin Osuch MSc
biolog
Dr. Magdalena Alejska
starszy specjalista biolog
Katarzyna Tomela MSc
research developer
Dr. Ireneusz Stolarek
adiunkt
Przy Zakładzie afiliowana jest:
Pracownia Genomiki
Kierownik: dr Luiza Handschuh
dr Jan Podkowiński, dr Paweł Wojciechowski (1/2 etatu), dr Agnieszka Żmieńko
Pracownia Hodowli Komórkowych i Tkankowych
Kierownik: dr Paweł Stróżycki
Hanna Glapiak, inż. Nelli Malinowska, dr Mariola Piślewska-Bednarek
Katarzyna Nowis MSc
PhD student
Cezary Odrzygóźdź MSc BEng.
PhD student / biologist
Małgorzata Marszałek-Zeńczak MSc
PhD student / biologist
Anastasiia Satyr MSc
PhD student
Michał Zeńczak MSc BEng.
PhD student
non-coding RNA, RNA modifications, ribonucleases, extracellular vesicles, RNA transport, deaminases, chromatin, genomics, population genetics, archaeogenomics
mgr Anastasiia Zaremba
PhD student
Annasha Dutta MSc
PhD student
Strona zrobiona w kreatorze stron internetowych WebWave
Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl
Sekretariat Dyrektora, tel: 61 852 89 19