Dr. habil. Marcin K. Chmielewski
Head of Department
chmielewskimk@ibch.poznan.pl
ext.1257
Magdalena Paluch MSc
PhD student
Anna Stasińska MSc
PhD student
Dominika Krygier MSc, BEng
specialist chemist
Dr. Jolanta Brzezińska
adiunkt
Mickiewicz, A.; Sarzyńska, J.; Miłostan, M.; Kurzyńska-Kokorniak, A.; Rybarczyk, A.; Łukasiak, P.; Kuliński, T.; Figlerowicz, M.; Błażewicz, J.Modeling of the catalytic core of Arabidopsis thaliana Dicer-like 4 protein and its complex with double-stranded RNA.Comput. Biol. Chem. 66, 44–56 (2017),
Baranek, Małgorzata; Belter, Agnieszka; Naskręt-Barciszewska, Mirosława Z.; Stobiecki, Maciej; Markiewicz, Wojciech T.; Barciszewski, Jan,Effect of small molecules on cell reprogramming.Mol. BioSyst. 13, 277–313 (2017),
Stokowa-Sołtys, K.; Barbosa, N. A.; Kasprowicz, A.; Wieczorek, R.; Gaggelli, N.; Gaggelli, E.; Valensin, G.; Wrzesiński, J.; Ciesiołka, J.; Kuliński, T.; Szczepanik, W.; Jeżowska-Bojczuk, M. Studies of viomycin, an anti-tuberculosis antibiotic: copper(II) coordination, DNA degradation and the impact on delta ribozyme cleavage activity.Dalt. Trans. 45, 8645–8658 (2016),
Fedoruk-Wyszomirska, A.; Markiewicz, W. T.; Barciszewski, J.New inhibitors of DNA methyltransferase 1 based on cytosine scaffold.BioTechnologia 4, 323–325 (2016),
Baranek, M.; Markiewicz, W. T.; Barciszewski, J.Selected small molecules as inducers of pluripotency.Acta Biochim. Pol. 63, 709–716 (2016),
Rypniewski, W.; Banaszak, K.; Kuliński, T.; Kiliszek, A.Watson–Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.RNA, 22, 22–31 (2016),
Brzezinska, J.; Markiewicz, W. T.Non-Nucleosidic Analogues of Polyaminonucleosides and Their Influence on Thermodynamic Properties of Derived Oligonucleotides.Molecules 20, 12652–12669 (2015),
Barciszewski, J.; Marquez, V. E.; Vasseur, J.-J.; Markiewicz, W. T.Chemical Biology of Nucleic Acids.ACS Chem. Biol. 10, 1358–1361 (2015),
Mickiewicz, A.; Sarzyńska, J.; Miłostan, M.; Kurzyńska-Kokorniak, A.; Rybarczyk, A.; Łukasiak, P.; Kuliński, T.; Figlerowicz, M.; Błażewicz, J.Modeling of the catalytic core of Arabidopsis thaliana Dicer-like 4 protein and its complex with double-stranded RNA.Comput. Biol. Chem. 66, 44–56 (2017)
High-efficiency resins for solid-phase synthesis of biomolecules. NCRD – PBS1
Development of method of chemical synthesis of bio-active triphosphates using thermolabile protecting. NSC – OPUS 4
Synthesis and characterization of novel functional organic silicon compounds as silica functionalising agent. NSC – OPUS 5
Thermolytic fluorescent dyes in nucleic acid labelling. co-funded by the European POIR.01.01.01-00-0027/17-00. 01.10.2017 – 30.09.2020 head of the project
“Regulated Assembly of Molecular Machines for DNA Repair: a Molecular Analysis Network” (DNARepairMan) as part of Innovative Training network supported through EU Horizon 2020 Marie Sklodowska-Curie Action under project number H2020-MSCA-ITN-2016 [DNAREPAIRMAN - 722433]. 31.01.2017-30.01.2020 project executive
research in chemical synthesis of biopolymers such as nucleic acids, peptides, carbohydrates and lipids.
application of original thermocyclization reaction in wider aspect of chemical synthesis.
Thermolability as tools in design of protecting groups, fluorescent labels, thermo-dependent catalysts and in polymerization reactions.
investigate in chemistry of examined compounds, to define the mechanism of observed processes and to obtain useful materials applicable in area of Life Sciences.
instrumental analysis using PVA capillary electrophoresis, High Pressure Liquid Chromatography (HPLC) with UV-Vis, fluorescence and korona detectors.
Strona zrobiona w kreatorze stron internetowych WebWave
Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl
Sekretariat Dyrektora, tel: 61 852 89 19