Dr. habil. Kamilla Bąkowska-Żywicka
Head of Department
bakowska@ibch.poznan.pl
Phone: 61 8291866
Anna Wasilewska MSc
PhD student
Piotr Pietras MSc, BEng.
PhD student
Klementyna Marciniak MSc, BEng.
biologist/ PhD student
Dr. Anna Mleczko
biologist
mgr inż. Kamila Pepłowska
biologist
mgr inż. Julian Zacharjasz
biologist
Dr. Piotr Machtel
asystent
Mleczko AM, Machtel P, Walkowiak M, Wasilewska A, Pietras PJ, Bąkowska-Żywicka K. Levels of sdRNAs in cytoplasm and their association with ribosomes are dependent upon stress conditions but independent from snoRNA expression. Sci Rep. 2019 Dec 5;9(1):18397. doi: 10.1038/s41598-019-54924-2.
Mleczko AM, Celichowski P, Bąkowska-Żywicka K. Transfer RNA-derived fragments target regulate ribosome-associated aminoacyl-transfer RNA synthetases. Biochim Biophys Acta Gene Regul Mech. 2018 Jun 6. pii: S1874-9399(17)30380-2. doi: 10.1016/j.bbagrm.2018.06.001
Bąkowska-Żywicka K, Mleczko AM, Kasprzyk M, Machtel P, Żywicki M, Twardowski T. The widespread occurrence of tRNA-derived fragments in Saccharomyces cerevisiae. FEBS Open Bio. 2016 Oct 21;6(12):1186-1200. doi: 10.1002/2211-5463.12127
Mleczko AM, Bąkowska-Żywicka K. When small RNAs become smaller: emerging functions of snoRNAs and their derivatives. Acta Biochim Pol. 2016;63(4):601-607.
Bąkowska-Żywicka K, Kasprzyk M, Twardowski T. tRNA-derived short RNAs bind to Saccharomyces cerevisiae ribosomes in a stress-dependent manner and inhibit protein synthesis in vitro. FEMS Yeast Res. 2016 Sep;16(6). pii: fow077
Machtel P, Bąkowska-Żywicka K, Żywicki M. Emerging applications of riboswitches – from antibacterial targets to molecular tools. J Appl Genet. 2016 Nov;57(4):531-541
Mleczko AM, Celichowski P, Bąkowska-Żywicka K. Ex-translational function of tRNAs and their fragments in cancer. Acta Biochim Pol. 2014;61(2):211-6.
Pircher A, Bakowska-Zywicka K, Schneider L, Zywicki M, Polacek N. An mRNA-derived noncoding RNA targets and regulates the ribosome. Mol Cell. 2014 Apr 10;54(1):147-155. doi: 10.1016/j.molcel.2014.02.024
Zywicki M, Bakowska-Zywicka K, Polacek N. Revealing stable processing products from ribosome-associated small RNAs by deep-sequencing data analysis. Nucleic Acids Res. 2012 May;40(9):4013-24. doi: 10.1093/nar/gks020
The research profile of the Functional Transcriptomics Team includes the identification and characterization of molecular mechanisms of RNA-based gene expression regulation in model pro- and eukaryotic organisms, as a response to environmental changes.
Our research interest includes the following topics:
identification, characterization and determination of the regulatory potential of small ribosome-associated noncoding RNAs (rancRNA) in Saccharomyces cerevisiae under various environmental conditions, with particular emphasis on heterogeneity of ribosomes,
identification of riboswitches which regulate transcription and translation in model bacterium Bacillus subtilis,
comprehensive characterization of changes in the transcriptional, translational and regulatory activity induced in response to antibiotic stress and culture in infectious conditions in the drug-resistant strain Staphylococcus aureus, with special emphasis on the therapeutic potential of regulatory RNAs.
Strona zrobiona w kreatorze stron internetowych WebWave
Institute of Bioorganic Chemistry,
Polish Academy of Sciences
Z. Noskowskiego 12/14
61-704 Poznań
tel centrala: (+48) 61 852 85 03
fax: (+48) 61 852 05 32
e-mail: ibch@ibch.poznan.pl
Sekretariat Dyrektora, tel: 61 852 89 19