Preliminary research on the chemical
programming of fungi using Ramularia collo-cygni as a model. The aim of the
project was to create and optimise a method for producing new analogues of
fungal metabolites with potential bioactivity. Preliminary results on the
biosynthetic pathways of rubellin metabolites were confirmed by spectral observation
of the key intermediate, chrysophanol, which was recently published. Several
new rubellin derivatives have also been observed - Miniatura 4 -
2020/04/X/NZ1/01959 (PI dr. Dorota Jakubczyk)