In the January issue of Cell Reports, an article titled Interrogation of RNA-bound proteome with XRNAX illuminates molecular alterations in the mouse brain affected with dysmyelination was published, authored by Marta Sztachera, MSc Eng., Weronika Wendlandt-Stanek, PhD, Luiza Stanaszek, PhD, DSc, Michał Smuszkiewicz, MSc, Dorota Wronka, MSc Eng., Remigiusz Serwa, PhD, and Monika Piwecka, PhD.

The publication presents the results of a high-throughput analysis of the RNA-protein interactome in the brains of mice with a myelination defect. This pioneering experimental study enhances our understanding of RNA-binding protein functions in the context of molecular changes in neurological diseases.

The study was conducted by researchers from the Department of Non-Coding RNAs at IBCH PAS in collaboration with partners from the Mossakowski Medical Research Institute PAS and the International Institute of Molecular Mechanisms and Machines (IMol) PAS.

Link to the article: https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01446-3

We encourage you to read it!