Dofinansowanie ze środków budżetu państwa
Deklaracja dostępności
Dr. hab. Agnieszka Kiliszek, prof. IBCH PAS Head of Department kiliszek@ibch.poznan.pl ext. 1278
prof. dr hab. Wojciech Rypniewski profesor instytutu
mgr Martyna Mateja-Pluta doktorant
mgr Faizan Faizan doktorant
Equal contribution - #; Corresponding authors - * Błaszczyk, L. # , Ryczek, M. # , Das, M. # , Mateja-Pluta, M., Bejger, M., Śliwiak, J., Nakatani, K., Kiliszek*, A. A ntisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Research , (2024) 52 ( 11 ): 6707–6717. DOI: 10.1093/nar/gkae376 Kiliszek, A., & Rypniewski, W. The emergence of biological homochirality.Acta biochimica Polonica, (2023) 70: 481–485. DOI: 10.18388/abp.2020_6914 Kiliszek, A., Rypniewski, W., Błaszczyk, L.Exploring structural determinants and the role of nucleolin in formation of the long-range interaction between untranslated regions of p53 mRNA.RNA, (2023) 29:630-643. DOI: 10.1261/rna.079378.122 Kiliszek, A.*, Pluta, M., Bejger, M., & Rypniewski*, W. Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair.RNA (2023) 29:44–54. DOI: 10.1261/rna.079414.122 Ryczek, M., Pluta, M., Błaszczyk, L., Kiliszek, A. Overview of Methods for Large- Scale RNA Synthesis.Appl. Sci. (2022) 12: 1543. DOI: 10.3390/app12031543 Kiliszek, A., Błaszczyk, L., Bejger, M., & Rypniewski, W. Broken symmetry between RNA enantiomers in a crystal lattice.Nucleic Acids Research (2021) 49:12535–12539. DOI: 10.1093/nar/gkab480 Nekvinda, J., Różycka, D., Rykowski, S., Wyszko, E., Fedoruk-Wyszomirska, A., Gurda, D., Orlicka-Płocka, M., Giel-Pietraszuk, M., Kiliszek, A., Rypniewski, W., Bachorz, R., Wojcieszak, J., Grüner, B., & Olejniczak, A. B. Synthesis of naphthalimide-carborane and metallacarborane conjugates: anticancer activity, DNA binding ability.Bioorganic Chem. (2020) 94:103432. DOI: 10.1016/j.bioorg.2019.103432 Mukherjee, S., Blaszczyk, L., Rypniewski, W., Falschlunger, C., Micura, R., Murata, A., Dohno, C., Nakatani, K.*, Kiliszek, A.* Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.Nucleic Acids Res. (2019) 47:10906-10913. DOI: 10.1093/nar/gkz832 Nowacka M., Fernandes H., Kiliszek A., Bernat A., Lach G., Bujnicki J.M. Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com.Plos One (2019) 47:10906-10913. DOI: 10.1371/journal.pone.0214481 Kiliszek A., Rypniewski W., Rzad K., Milewski S., Gabriel I. Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. Journal of Structural Biology (2019) 205: 26-33. DOI: 10.1016/j.jsb.2019.02.001 Li J., Nakamori M., Matsumoto J., Murata A., Dohno C., Kiliszek A., Taylor,K., Sobczak K., Nakatani K. A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models.Chem. Eur. J. (2018) 24:18115-18122. DOI: 10.1002/chem.201804368 Kiliszek A.#, Błaszczyk L.#, Kierzek R. and Rypniewski W. Stabilization of RNA hairpin structures for crystallographic studies.Nucleic Acids Res. (2017) 45:e92. DOI: 10.1093/nar/gkx122 Błaszczyk L., Rypniewski W and Kiliszek A. Structures of RNA repeats associated with neurological diseases. WIREs RNA, (2017) 8:UNSP e1412 Invited Article. DOI: 10.1002/wrna.1412 Kiliszek A., Banaszak K., Dauter Z. and Rypniewski W. The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches—toward anti-sense therapy against TREDs. Nucleic Acids Res. (2016) 44:1937-1943. DOI: 10.1093/nar/gkv1513 Rypniewski W., Banaszak K., Kulinski T. and Kiliszek A. Watson-Crick-like pairs in CCUG repeats. Evidence for tautomeric shifts or protonation.RNA (2016) 22:22-31. DOI: 10.1261/rna.052399.115 Kiliszek A. and Rypniewski W. Structural studies of CNG repeats.Nucleic Acids Res. (2014) 42:8189-99. DOI: 10.1093/nar/gku536
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