Department of Plant Functional Metabolomics

Prof. Paweł Bednarek

Head of Department

bednarek@ibch.poznan.pl
ext. 1167

Research activity

Research area

Tryptophan metabolism in the immunity of the model plant species Arabidopsis thaliana.
Evolution of secondary metabolites in the Brassicaceae family.
Secondary metabolism pathways implicated in the immunity of the model grass Brachypodium distachyon.
Function of plant secondary metabolites in growth promotion induced by microbial endophytes.

Keywords

Secondary metabolites,
plant immunity,
tryptophan metabolism,
glucosinolates, Brassicaceae,
Arabidopis thaliana,
Brachypodium distachyon

Research Projects

Characterisation of key mechanisms for the coordination and prioritisation of barley responses to simultaneous biotic and abiotic stresses - a multiomics approach. NCN OPUS 23 - Principal investigator Anna Piasecka
Molecular basis of glucosinolate modification and activation in the immunity of Brassicaceae species
Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of bioactive sulfur-containing compounds from Brassicaceae plants. (National Science Center OPUS).
Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites. (National Science Center OPUS).

Selected publications

Frerigmann, H., Piotrowski, M., Lemke, R., Bednarek, P., and Schulze-Lefert, P. (2021). A Network of Phosphate Starvation and Immune-Related Signaling and Metabolic Pathways Controls the Interaction between Arabidopsis thaliana and the Beneficial Fungus Colletotrichum tofieldiae. Mol. Plant-Microbe Interact. 34, 560-570.
Pastorczyk-Szlenkier, M., and Bednarek, P. (2021). UGT76B1 controls the growth-immunity trade-off during systemic acquired resistance. Molecular Plant 14, 544–546.
Sugiyama, R., Li, R., Kuwahara, A., Nakabayashi, R., Sotta, N., Mori, T., Ito, T., Ohkama-Ohtsu, N., Fujiwara, T., Saito, K., Nakano, R.T., Bednarek, P., and Hirai, M.Y. (2021). Retrograde sulfur flow from glucosinolates to cysteine in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 118, e2017890118.
Winkelmüller, T.M., Entila, F., Anver, S., Piasecka, A., Song, B., Dahms, E., Sakakibara, H., Gan, X., Kułak, K., Sawikowska, A., Krajewski, P., Tsiantis, M., Garrido-Oter, R., Fukushima, K., Schulze-Lefert, P., Laurent, S., Bednarek, P., and Tsuda, K. (2021). Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species. Plant Cell 33, 1863-1887.
Wolinska, K.W., Vannier, N., Thiergart, T., Pickel, B., Gremmen, S., Piasecka, A., Piślewska-Bednarek, M., Nakano, R.T., Belkhadir, Y., Bednarek, P., and Hacquard, S. (2021). Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots. Proc. Natl. Acad. Sci. USA 118, e2111521118.
Czerniawski, P., Piasecka, A., and Bednarek, P. (2021). Evolutionary changes in the glucosinolate biosynthetic capacity in species representing Capsella, Camelina and Neslia genera. Phytochemistry 181, 112571.
Kosaka, A., Pastorczyk, M., Piślewska-Bednarek, M., Nishiuchi, T., Ono, E., Suemoto, H., Ishikawa, A., Frerigmann, H., Kaido, M., Mise, K., Bednarek, P., and Takano, Y. (2021). Tryptophan-derived metabolites and BAK1 separately contribute to Arabidopsis postinvasive immunity against Alternaria brassicicola. Scientific Reports 11, 1488.
Pastorczyk, M., Kosaka, A., Pislewska-Bednarek, M., Lopez, G., Frerigmann, H., Kulak, K., Glawischnig, E., Molina, A., Takano, Y., and Bednarek, P. (2020). The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity. New Phytologist 225, 400-412.
Hématy, K., Lim, M., Cherk, C., Piślewska-Bednarek, M., Sanchez-Rodriguez, C., Stein, M., Fuchs, R., Klapprodt, C., Lipka, V., Molina, A., Grill, E., Schulze-Lefert, P., Bednarek, P., and Somerville, S. (2020). Moonlighting Function of Phytochelatin Synthase1 in Extracellular Defense against Fungal Pathogens. Plant Physiology 182, 1920-1932.
Piślewska-Bednarek M., Nakano R.T., Hiruma K., Pastorczyk M., Sanchez-Vallet A., Singkaravanit-Ogawa S., Ciesiołka D., Takano Y., Molina A., Schulze-Lefert P., Bednarek P. (2018). Glutathione Transferase U13 Functions in Pathogen-Triggered Glucosinolate Metabolism. Plant Physiology 176, 538-551.
Sopeña‐Torres, S., Jordá, L., Sánchez‐Rodríguez, C., Miedes, E., Escudero, V., Swami, S., López, G., Piślewska‐Bednarek, M., Lassowskat, I., Lee, J., Gu, Y., Haigis, S., Alexander, D., Pattathil, S., Muñoz‐Barrios, A., Bednarek, P., Somerville, S., Schulze‐Lefert, P., Hahn, M.G., Scheel, D., and Molina, A. (2018). YODA MAP3K kinase regulates plant immune responses conferring broad‐spectrum disease resistance. New Phytologist 218, 661-680.
Nakano, R.T., Piślewska-Bednarek, M., Yamada, K., Edger, P.P., Miyahara, M., Kondo, M., Böttcher, C., Mori, M., Nishimura, M., Schulze-Lefert, P., Hara-Nishimura, I., and Bednarek, P. (2017). PYK10 myrosinase reveals a functional coordination between endoplasmic reticulum bodies and glucosinolates in Arabidopsis thaliana. The Plant Journal 89, 204-220.
Fukunaga, S., Sogame, M., Hata, M., Singkaravanit-Ogawa, S., Piślewska-Bednarek, M., Onozawa-Komori, M., Nishiuchi, T., Hiruma, K., Saitoh, H., Terauchi, R., Kitakura, S., Inoue, Y., Bednarek, P., Schulze-Lefert, P., and Takano, Y. (2017). Dysfunction of Arabidopsis MACPF domain protein activates programmed cell death via tryptophan metabolism in MAMP-triggered immunity. The Plant Journal 89, 381-393.
Pastorczyk, M. and Bednarek, P. (2016) The Function of Glucosinolates and Related Metabolites in Plant Innate Immunity. In Adv. Bot. Res. Kopriva, S. ed: Academic Press, pp. 171-198.
Frerigmann, H., Piślewska-Bednarek, M., Sánchez-Vallet, A., Molina, A., Glawischnig, E., Gigolashvili, T. and Bednarek, P. (2016) Regulation of Pathogen-Triggered Tryptophan Metabolism in Arabidopsis thaliana by MYB Transcription Factors and Indole Glucosinolate Conversion Products. Molecular Plant, 9, 682-695.

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Department of Plant Functional Metabolomics

Researchers:

Technical Staff:

PhD students

Research activity

Research area

Keywords

Research Projects

Selected publications

Adres

Address

Department of Plant Functional Metabolomics

Researchers:

Technical Staff:

PhD students

Research activity

Research area

Keywords

rys.1

Rys. 2

Rys. 3

Rys. 4

Research Projects

Selected publications

Adres

Address