Department Of Molecular Genetics

prof. dr hab. Piotr Kozłowski

Prof. Piotr Kozłowski

Head of Department

kozlowp@ibch.poznan.pl
ext.​ ​​1261

Researchers:

Dr. Anna Jasińska
adiunkt

Dr. Malwina Suszyńska
adiunkt

Dr. ​Daniel Kuźnicki
adiunkt

Dr. Paulina Gałka-Marciniak
adiunkt

Research activity

Research area
  • Cancer genetics
  • Methodology of CNV polymorphism analysis
  • Polymorphism and somatic variation of miRNA genes
  • The role of circRNA in myotonic dystrophy type 1 (DM1)
Keywords
  • Cancer genetics
  • Copy number variation polymorphism (CNV)
  • Multiplex ligation-depent probe amplification (MLPA)
  • miRNA
  • lncRNA
  • circRNA

Research Projects

  • The effect of cancer somatic mutations in miRNA genes on the functioning of these genes and their potential role in cancer. NSC SONATA16, 2020/39/D/NZ2/03106, PI: Paulina Galka-Marciniak, PhD.
  • Identification of cancer-driver mutations in non-coding parts of protein-coding genes and long non-coding RNA genes. NSC OPUS20, 2020/39/B/NZ5/01970, PI: Piotr Kozlowski, Prof.
  • Cancer Genetics: Identification and Analysis of Oncogenic Somatic Mutations in miRNA. Fulbright U.S. Student Researcher 2020/2021. PI: Piotr Kozlowski, Prof.
  • Antibiotic resistance genes and integrons as indicators of biotic pollution and the resistance burden of Arctic ecosystems. NSC SONATINA4, 2020/36/C/NZ9/00221, PI: Nicoletta Makowska-Zawierucha, PhD.
  • Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of cancer. NSC MAESTRO 8, 2016/22/A/NZ2/00184 , PI: Piotr Kozlowski, Prof.
  • Analysis of BARD1 gene in genetic predisposition to breast cancer- utilization of unique strategy of association of founder mutations. NSC OPUS9, 2015/17/B/NZ2/01182, PI: Piotr Kozlowski, Prof.
  • Expression of circular RNAs in myotonic dystrophy type 1- implication to pathogenesis. NSC PRELUDIUM 11, 2016/21/N/NZ5/00508, PI: Karol Czubak, PhD.
  • The APOBEC3B deletion- analysis of its role in familial breast cancer predisposition of its consequences on mRNA level. NCN PRELUDIUM10, 2015/19/N/NZ5/02247, PI: Katarzyna Klonowska, PhD.
  • Elucidation of the molecular causes and effects of elevated circular RNAs expression levels in myotonic dystrophy type 1 (DM1). NCN OPUS7, 2014/13/B/NZ5/03214, PI: Marzena Wojciechowska, Prof.
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