Dofinansowanie ze środków budżetu państwa
Deklaracja dostępności
Agreement number
Title
Principal Investigator
Start date
End date
Project type
N N401 066338
A new method of global analysis of modified nucleic acid components and its application in clinical diagnosis of cancer
Mirosława Naskręt-Barciszewska
2010-02-21
2013-04-20
Supervisory project; call no. 40
N N302 260938
Modern antisense technologies in myotonic dystrophy therapy
Krzysztof Sobczak
2010-04-09
2013-10-30
Supervisory project; call no. 38
N N301 523038
Validation of microRNA interactions with mRNA in the context of pathogenesis and therapy of some hereditary neurological diseases
Edyta Kościańska
2010-04-27
2013-07-31
N N401 595538
Search and analysis of non-coding RNA specific for malignant brain tumors
Katarzyna Rolle
2010-05-06
2013-05-05
N N310 043738
Correlation of epigenetic modification of DNA and histone proteins as a mechanism of plant response to herbicidal stress conditions
Tomasz Twardowski
2010-05-17
2013-06-28
N N301 411238
New enantiomeric forms of hammerhead ribozymes as therapeutic agents
Jan Barciszewski
2013-05-16
N N301 392139
Identification of full ABCG Medicago truncatula transporters and initial functional analysis of selected genes involved in response to biotic stress
Michał Jasiński
2010-09-23
2013-04-22
Supervisory project; call no. 39
N N310 309839
Alternative splicing in maize induced by herbicidal stress
2010-10-22
2013-10-21
N N302 434439
104/5000Analysis of the effect of genetic inactivation of homocysteine metabolizing enzymes thiolactone on the mouse proteome
Hieronim Jakubowski
2010-11-12
2013-04-11
N N204 430640
Analysis of human plasma fibrinogen N-homocysteinylation by chemical methods and mass spectrometry in the context of cardiovascular diseases
Łukasz Marczak
2011-04-20
2014-04-19
N N401 572140
Analysis of the interaction of proteins with mutated transcripts of genes involved in TREDs diseases
Marzena Wojciechowska
2011-05-04
2015-01-03
N N301 707040
RNA quadruplexes built from AGG, CGG and UGG trinucleotide repeats
Zofia Gdaniec
2011-05-06
2014-08-05
N N301 788440
Studies on the functional nature of the RNA structure of influenza virus aimed at inhibiting its multiplication
Elżbieta Kierzek
2014-05-05
N N302 633240
Testing of non-specific effects caused by RNA and microRNA interference technology reagents
Marta Olejniczak
2015-01-05
Regulation of Huntingtin gene expression by RNA duplexes
Włodzimierz Krzyżosiak
N N310 769040
Small non-coding RNA and changes in plant' degradom as the answer mechanism on stress conditions
2011-05-19
2014-05-18
N N310 721640
Study of the relationship between the phenolic secondary metabolite profile and the level of expression of the phenylpropanoid pathway genes in narrow-leafed lupine seedlings when assessing resistance to infection by a fungal pathogen
Maciej Stobiecki
2011-05-23
2014-05-22
N N401 597840
The effect of N-homocysteinylation of histone proteins on epigenetic regulation of human gene expression
2011-05-27
2013-05-26
2011/01/B/ST5/06414
Aryl nucleoside phosphoramidates - a new generation of anti-HIV pronucleotides
Jacek Stawiński
2011-12-01
2015-11-30
Opus 1
2011/01/B/NZ1/04429
RNA clip forms of importance in biology and pathogenesis. Crystallographic analysis
Wojciech Rypniewski
2011-12-06
2015-06-05
2011/01/N/NZ2/00025
The use of tandem mass spectrometry with collision-induced dissociation techniques for profiling and structural analysis of phenolic secondary metabolites in multicomponent extracts of plant material
Anna Wojakowska
2013-06-05
Preludium 1
2011/01/B/NZ1/03417
Mechanisms contributing to the development of thrombosis in patients with cystathionine β-synthesis deficiency
2014-12-05
2011/01/B/NZ5/02773
Identification of new genes that play an important role in the process of cancer in common human cancers
Piotr Kozłowski
2012-02-20
2011/01/B/NZ2/04816
Copy number polymorphism as an important mechanism conditioning the variability of plant genomes. Impact of endogenous (RNA interference) and exogenous (stress) factors on the frequency and location of mutations associated with copy number polymorphism
Marek Figlerowicz
2011-12-07
2015-06-06
2011/01/N/NZ3/04602
Study of the secondary structure and function of BC200 RNA in human brain tumors
Patrycja Sosińska-Zawierucha
2013-12-06
2011/01/D/NZ1/03478
RNA chaperone activity of HIV-2 Gag and nuclocapsid proteins: implications for the design of the new retroviral inhibitors
Katarzyna Pachulska-Wieczorek
Sonata 1
2011/01/B/ST6/07021
High-performance calculations for next-generation DNA sequencing
Aleksandra Świercz
2011-12-08
2013-12-07
2011/01/D/NZ9/03631
Analysis of the epigenome and proteome of maize (Zea mays), a line resistant and sensitive to herbicide
Agata Tyczewska
2011-12-12
2015-12-11
2011/01/B/NZ4/04936
The new generation of anti-cancer pro-nucleotides
2011-12-16
2015-12-15
2011/01/N/NZ9/02900
Searching for sequences regulating the splicing process under herbicidal stress in common maize
Joanna Gracz-Bernaciak
2014-10-15
2011/03/B/NZ1/00576
New methods for the determination of RNA secondary structure, tools towards studies biological activities of RNAs
Ryszard Kierzek
2012-08-02
2015-08-01
Opus 2
2011/03/B/NZ1/02840
ABC transporters as modulators of Medicago truncatula symbiotic interactions
2012-08-16
2015-08-15
2011/03/B/NZ1/03259
Sequential preferences of ribonucleases of the human microRNA biogenesis pathway
2012-08-17
2015-08-16
2011/03/B/NZ1/01238
Structural proteomics of mulberry silkworm hemolymph
Grzegorz Bujacz
2012-08-27
2015-08-26
2011/03/B/ST5/01098
New approaches towards modulating selective and functional activities of antisense oligonucleotides
2012-08-29
2015-05-28
2011/03/B/ST5/03102
Development of stereospecific phosphorylating agents containing nucleophilic catalytic groups
Michał Sobkowski
2016-02-28
2012/05/D/ST5/03599
New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological activity of nucleic acids
Anna Pasternak
2013-02-07
2016-02-06
2012/05/D/NZ2/02238
Analysis of the plasma proteome in chronic kidney disease in the context of progressive cardiovascular disease
Magdalena Łuczak
2013-03-01
2016-09-30
Opus 4
Establishment of a novel scientific workshop enabling complex analysis of RNA degradome - elaboration of innovative methods for the identification of RNA degradants and the assessment of their functional potential
Paulina Jackowiak
2016-08-31
Sonata 3
2012/05/N/NZ1/0191918.03.2013
The study of structure of miR21 RNA and its precursor - the basis marker of brain tumors in human
Agnieszka Belter
2013-03-18
2015-03-17
Preludium 3
2012/06/A/NZ1/00094
RNA toxicity in pathogenesis of polyglutamine diseases
Maciej Figiel
2013-03-22
2019-03-21
Maestro 3
2012/05/N/NZ7/02157
Study of the relationship between the chemical structure and the activity of new flavonoid derivatives as inhibitors of bacterial tyrosyl tRNA synthetase
Mirosława Skupińska
2013-03-27
2015-03-26
Preludium 4
2012/06/A/NZ9/00125
Multilevel approach to reveal elucive molecular basis of herbicide stress response in maize
2013-05-07
2019-11-06
2012/07/E/NZ2/04098
Plant secondary metabolites controlling microbial colonizers
Paweł Bednarek
2013-07-11
2018-10-10
Sonata Bis 2
2012/07/B/ST5/03035
Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups
Marcin K.Chmielewski
2013-07-19
2017-07-18
2012/07/B/ST6/01537
Study of the possibilities and limitations of the use of Petri nets for modeling and analysis of complex biological systems on the example of the process of formation and development of atherosclerosis in the human body
Piotr Formanowicz
2013-07-25
2017-07-24
2013/08/M/NZ1/01062
Conserved RNA structural motifs in influenza virus: toward revealing viral RNA functions
2013-08-28
2017-05-27
Harmonia 4
2013/08/A/ST5/00295
Structure defined oligonucleotides for revealing fundamental insights into structure and function of RNAs
2019-08-27
Maestro 4
2013/08/T/NZ4/00712
Molecular and behavioral characteristics of new mouse types of cerebellospinal ataxia type 3 (SCA3)
Paweł Świtoński
2013-10-01
2014-09-30
Etiuda 1
2013/09/B/NZ1/01884
The role of the 5' non-coding regions of p53 mRNA transcripts, which are synthesized from various transcription promoters and use alternative initiation sites in generating p53 protein isoforms
Jerzy Ciesiołka
2014-02-13
2017-08-12
Opus 5
2013/09/B/NZ5/02794
Role of homocysteine in pathogenesis of thrombosis
2017-02-12
2013/09/B/NZ1/03359
Ribozymes as a new tool for mitochondrial genome research
2014-03-11
2017-03-10
2013/09/N/NZ2/02080
Evolution of Brassicaceae plant secondary metabolites essential in plant immunity
Karolina Kułak
2014-03-14
2016-09-13
Preludium 5
2013/09/D/NZ1/03364
Evolutionary modeling physicochemical conditions for overexpression of viral replicons in plant liquid cultures
Radosław Pilarski
2014-04-03
2018-04-02
Sonata 5
2913/10/M/NZ3/00260
ABA transport in legumes - between drought stress responses and nitrogen fixation efficiency
2014-05-19
2017-11-18
Harmonia 5
2013/10/E/NZ1/00741
Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification
2014-07-02
2018-04-01
Sonata Bis 3
2013/11/N/NZ1/92429
Key elements of miRNA precursors conditioning the release of homogeneous siRNAs from shRNA-miR vectors
Paulina Gałka-Marciniak
2014-07-04
2016-07-03
Preludium 6
2013/10/E/NZ4/00621
Defining new neurodegeneration mechanisms using the first SCA3/MJD knock-in mouse model
2014-07-08
2020-07-07
2013/11/B/NZ1/00091
Mechanisms and consequences of homocysteine incorporation into proteins in humans
2014-07-28
2017-07-27
Opus 6
2014/12/W/NZ2/00466
Dynasty and population of the Piast State in view of the integrated historical, anthropological and genomic studies
2014-12-10
2021-12-09
Symfonia 2
2014/13/D/NZ1/00061
Changes in the ribosomal protein composition and in the ribosome-associated small noncoding RNAs in Saccharomyces cerevisiae as a response to environmental stress
Kamilla Bąkowska-Żywicka
2015-01-22
2018-01-21
Sonata 7
2014/13/B/NZ7/02291
Kinetin riboside and its derivatives-analysis of apoptotic properties and mechanism of action in brain tumor cells
Eliza Wyszko
2015-01-23
2019-10-22
Opus 7
2014/13/B/ST5/04144
RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression
2018-07-22
2014/13/B/NZ2/03837
Elucidation of the mechanisms that induce copy number polymorphism of large genome fragments and of the relations between this phenomenon and metabolic gene cluster formation and evolution in plants
2015-02-26
2019-07-25
2014/13/B/NZ5/03214
Understanding the mechanism of action for small molecule kinase inhibitors inalleviating myotonic dystrophy type I (DMl) pathomechanism
2015-03-11
2019-07-10
2014/15/B/NZ1/01880
Mechanisms underlying the targeting ofcoding sequence repeats by microRNA-likeinhibitors
Agnieszka Fiszer
2015-07-15
2019-07-14
Opus 8
2014/15/B/NZ9/02312
Identification of molecular mechanisms involved in soybean's cold stress response in temperate climate conditions
2015-07-17
2020-01-16
2014/15/D/NZ2/02305
Identification of circular RNAs and protein factors involved in their biogenesis in a model plant, Arabidopsis thaliana
Anna Philips
2015-07-21
2019-07-20
Sonata 8
2014/15/N/NZ5/01646
Role of hyperhomocysteinemia in scent signalling in mice
Jacek Wróblewski
2015-08-25
2019-08-24
Preludium 8
2014/15/N/NZ5/01647
Pathophysiological consequences of histone N-homocysteinylation in hyperhomocysteinemia caused by CBS deficiency
Izabela Bielińska / Lewandowska
2015/16/S/NZ1/00086
Degradation pathways of transcripts associated with human diseases the basis of which is the expansion of microsatellite sequences
Karolina Drążkowska
2015-12-01
2019-03-11
Fuga 4
Structural studies ofproteins crucial for tick-mammal-pathogen interactions
Mariusz Jaskólski
2016-01-27
2020-01-26
Opus 9
2015/17/D/NZ5/03444
Long term survival and oxidative stress in hyperhomocysteinemia
Marta Sikora
2016-01-28
2020-07-27
Sonata 9
2015/17/D/NZ3/03625
Active transport systems as an element that controls the molecular cross-talk between symbionts during arbuscular mycorrhiza formation
Joanna Banasiak
2016-02-02
2020-02-01
2015/17/B/NZ1/00871
Molecular mechanisms underlying loss of a defensive metabolic pathway in a phylogenet ic clade of plant species closely related to Capsella rubella
2016-02-25
2019-07-24
2015/17/D/NZ5/03443
Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases
2021-02-24
2015 17/B/ST5/01467
Catalytic nucleic acids in of the new generation in the regulation of genetic information
2016-02-26
2020-02-25
2015/17/B/NZ2/01182
Analysis of the role of BARD1 gene in genetic predisposition to breast cancer -utilization of unique strategy of association analysis od founder mutations
2016-03-01
2021-08-31
2015/17/N/NZ3/03629
Imaging miRNA biogenesis pathway and cellular localization of RNA interference triggers
Martyna Urbanek-Trzeciak
2016-03-09
2019-12-08
Preludium 9
2015/17/N/NZ3/03626
Structure and function of Glod4 protein
Olga Utyro
2016-03-14
2020-03-13
2015/17/N/NZ2/01916
MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology
Emilia Kozłowska
2016-03-15
2021-03-14
2015/18/E/NZ2/00678
The use of genetic tools in experimental therapy of polyglutamine diseases
2016-04-18
2021-10-17
Sonata Bis 5
2015/18/M/NZ1/00406
Function of plant secondary metabolites in microbe-induced growth promotion
2016-05-13
2020-10-12
Harmonia 7
2015/19/B/NZ9/03548
The role of membrane transporters in the cytokinin signaling upon Legume- Rhizobia Symbiosis
2016-06-15
2020-12-14
Opus 10
2014/19/B/NZ2/02453
Identification of CAG repeat-binding proteins and imaging RNA-prorein interacrions in cells
Adam Ciesiołka
2016-06-20
2021-06-19
2015/19/B/NZ1/02803
In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza virus proliferation with modified antisense oligonucleotides, siRNAs and small molecule ligands
2020-06-19
2015/19/B/NZ2/02450
Molecular mechanism of atherosclerosis progression in chronic kidney disease
2021-12-19
2015/19/B/NZ1/02804
Role of microRNAs in regulation iron metabolism in Friedreich's ataxia
Marek Napierała
2016-07-14
2020-04-13
2015/19/N/NZ5/02246
Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues
Weronika Kotkowiak
2016-08-09
2018-02-08
Preludium 10
2015/19/N/NZ5/02247
The APOBEC3B deletion - analysis of its role in familial breast cancer predisposition and determination of its consequences on mRNA level
Katarzyna Klonowska
2019-08-08
2015/19/D/NZ5/02183
RAN translation at CAG repeats in spinocerebellar ataxia type 3
Magdalena Jazurek-Ciesiołka
2016-09-01
2023-02-28
Sonata 10
2016/20/W/ST5/00478
Supramolecular Peptide Organic Frameworks (POFs)
2016-11-10
2022-11-09
Symfonia 4
2015/19/B/NZ3/02412
Cytoplasmatic roadblocks in cell fate reprogramming: from players to molecular mechanisms
Rafał Ciosk
2016-11-30
2020-11-29
2016/21/B/NZ2/03468
Impact of noncoding RNAs on renal cell development and carcinogenesis
Jan Wrzesiński
2017-02-16
2021-08-15
Opus 11
2016/21/B/NZ1/02832
The role of protein factors that bind to the 5'non-coding region of human p53 mRNA in regulation of p53 expression at the translational level
2016/21/D/NZ3/00641
Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer
Patrick Perrigue
2017-02-17
2020-11-16
Sonata 11
2016/21/D/NZ5/01906
Bifunctional antisense oligonucleotides - optimization of alternative splicing regulation in cancer cell lines
Jolanta Lisowiec-Wąchnicka
2017-03-02
2021-03-01
2016/21/N/NZ5/00508
Ekspression of circular RNA in myotonic dystrophy type I - implications topathogenesis
Karol Czubak
2017-03-14
Preludium 11
2016/21/N/NZ1/00564
Catalytic RNS's as a tool for human mitochondrial biotechnology
Paweł Głodowicz
2017-03-15
2016/21/N/NZ1/00565
Modified siRNAs, ribozymes and cRISPR/Cas system as strategies for influenza A virus inhibition. Application and comparison of RNA-targeting methods
Julita Piasecka
2017-03-16
2021-03-15
2016/21/B/ST8/00477
New, multifunctional nanoparticles for combined photothermal and gene silencing cancer therapy
2017-04-13
2021-10-12
2016/22/E/NZ3/00426
RNA structures and interactions with Gag protein that specify Ty1 RNA functions during retrotransposon replication
2017-05-08
2022-12-07
Sonata Bis 6
2016/22/E/NZ1/00422
Unknown areas of activity of human ribonuclease Dicer
Anna Kurzyńska-Kokorniak
2022-05-07
2016/22/A/NZ2/00184
Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of cancer
2017-05-15
2022-05-14
Maestro 8
2016/23/D/NZ1/02565
How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of p53 protein - a master regulator of vital cellular functions
Leszek Błaszczyk
2017-08-17
2023-02-16
Sonata 12
2017/01/X/NZ2/00144
Copy number variation of Arabidopsis thaliana MSH2 gene - the structure of duplication, range of polymorphism in natural ecotypes and its impact on the expression of genes involved in DNA mismatch repair pathway
Agnieszka Żmieńko
2017-08-23
2018-08-22
Miniatura 1
2016/23/N/NZ1/02446
Designing a new method for direct identification and absolute quantification of premature transcription termination events, following the example of bacterial riboswitches
Piotr Machtel
2017-09-13
2020-09-12
Preludium 12
2017/01/X/ST5/00381
Synthesis of new pirymidine nucleoside dimers analogues containing a 1,2,3-triazole linkage of potential application in medicine
Dagmara Baraniak
2017-09-19
2018-09-18
2016/23/N/ST5/03024
N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules and their analogues
Magdalena Materna
2017-09-20
2019-12-19
2017/01/X/ST5/00577
New 3,6,9-trisubstituted 9-H-carbazole derivatives as potential fluorescent probes for the detection of DNA and RNA quadruplexes
Daniel Baranowski
2017-10-10
2018-10-09
2017/01/X/ST5/00589
The use of chemically modified RNA quadruplexes in antisense therapy
Dorota Gudanis
2017/01/X/ST5/00680
Synthesis of novel porphyrin derivatives with potential application in photodynamic therapy (PDT)
Zofia Jahnz-Wechmann
2017/24/C/NZ1/00219
Function of secondary structure of influenza A virus vRNA in ribonucleoproteincomplex during viral life cycle
Elżbieta Lenartowicz
2017-11-10
2021-11-09
Sonatina 1
2017/25/B/NZ7/00127
Structural determinants of anticancer properties of G-rich oligonucleotides
2018-01-30
2022-01-29
Opus 13
2017/25/B/NZ1/02269
Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method for next-generation sequencing based chemical mapping of RNA structure
2017/01/X/NZ2/01906
Exome analysis of acute myeloid leukemia patients
Luiza Handschuh
2018-02-09
2019-02-08
2017/25/N/NZ2/00221
Copy number polymorphism of microRNA genes in Arabidopsis thaliana accessions and its impact on the post-transcriptional regulation of their target genes' expression
Anna Samelak-Czajka
2018-02-14
2021-08-13
Preludium 13
2018/02/X/NZ2/02214
Mutagenesis of biosynthetic pathways for secondary metabolites of Brachypodium distachyon model grass
Karolina Krystkowiak
2018-02-19
2019-02-18
Miniatura 2
2017/25/B/ST5/00971
Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered modified nucleosides: ct6A, ms2ct6A, ges2U
2018-02-21
2022-02-20
2017/26/D/NZ2/00964
Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes
2018-04-13
2022-04-12
Sonata 13
2017/25/B/NZ3/02173
Functional crostallk between circRNAs and extracellular matrix (ECM) - the importance for glioblastoma stem cells (GSC) and epithelial-mesenchymal transition (EMT) in brain tumors
2018-04-16
2023-04-15
2017/25/B/NZ7/02162
Anti-aging properties of 4-N-furfyrylocytosine in age-differentiated eukaryotic cells, budding yeast and mouse model of aging
2018-04-17
2022-04-16
2017/26/E/NZ1/00950
Development of methodology aiming at stabilisation of RNA in a hairpin form for crystallographic studies
Agnieszka Kiliszek
2018-06-04
2023-06-03
Sonata Bis 7
2017/26/D/NZ1/01234
Caged bioluminogenic substrates for a selective molecular imaging of biochemical parameters in cancer
Jacek Kolanowski
2018-06-05
2023-06-04
2017/27/B/NZ1/01416
2018-06-29
2022-06-28
Opus 14
2017/26/D/NZ1/00887
Mechanisms of human gene expression regulation by uridilation
Zbigniew Warkocki
2018-07-02
2023-01-01
2017/27/B/NZ1/02201
The study of chitinolytic enzymes, aiming at constructing an artificial chitinosome
2018-09-03
2022-09-02
2017/27/B/NZ1/01090
Molecular basis of the selective transport fulfieled by plant ABCG proteins
2018-09-17
2021-09-16
2017/26/D/NZ2/01079
Contribution of gene copy number polymorphism to natural variation in response of Arabidopsis thaliana ecotypes to biotic stress
2022-09-16
2018/28/C/NZ1/00497
Pioneering structural and functional studies of miRNA G-quadruplexes
2018-09-20
2023-06-19
Sonatina 2
2017/26/E/NZ3/01004
The characteristic of the regulatory RNAs landscape in glioblastoma multiforme (GBM). Circular RNAs and micro RNA-like molecules as new players in gilomagenesis and GBM progression and their importance for glioblastoma stem cells
2018-10-15
2022-10-14
2018/02/X/NZ8/01334
The origin of the population living in today's Poland in the I-IV century- initial isotope analysis of strontium
Małgorzata Marcinkowska-Swojak
2018-11-02
2019-11-01
2018-02/X/NZ1/01797
Obtaining PR-10 isoforms from Hypericum perforatum, as potential melatonin receptors and mediators of phytohormone signal, and preliminary crystallographic characteristics of their complexes with natural ligands
Joanna Śliwiak
2018-12-03
2019-12-02
2018/02/X/NZ3/02233
Preliminary characterization of the function of ERD6 membrane protein in glucosinolate transport in Arabidopsis immunity
Marta Pastorczyk-Szlenkier
2018-12-19
2019-12-18
2018/02/X/ST5/02409
Synthesis of a new type of nucleotide analogues with P-N bond as potential anti-HIV pronucleotides
Joanna Romanowska
2019-01-04
2020-01-02
2018/29/B/NZ1/00293
Investigation of DNA double-strand break repair mechanisms in microsatellite regions using the CRISPR/Cas system
2019-01-14
2023-01-13
Opus 15
2018/02/X/NZ5/03028
Rescuing Friedreich’s ataxia phenotype by transcription progression
Julia Misiorek
2019-03-30
2020-03-29
2018/30/E/NZ1/00729
Inhibition of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa by targeting the enzyme dynamics
Krzysztof Brzeziński
2019-04-30
2024-04-29
Sonata Bis 8
2018/29/B/ST4/01498
Small molecule tools to investigate local microenvironment of proteins
2019-07-01
2023-06-30
2018/31/B/NZ3/03626
Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of bioactive sulfur-containing compounds from Brassicaceae plants
2019-08-01
2023-04-30
Opus 16
2018/31/N/ST5/03589
Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new structural motives
Justyna Gołębiewska
2019-08-30
2021-08-29
Preludium 16
2018/31/D/ST4/01467
NMR structural studies of 8-17 and I-R2 DNAzymes
Witold Andrałojć
2019-09-02
2023-09-01
Sonata 14
2018/31/B/NZ1/03580
Mechanisms and developmental roles of transcription termination
Takashi Miki
2019-09-03
2023-03-02
2018/31/B/NZ2/01940
Shedding new light on genome's dark matter: identification of novel long non-coding RNAs in zebrafish
Barbara Uszczyńska-Ratajczak
2018/31/D/NZ1/03630
Histidine Biosynthetic Pathway in Plants: Structural and Functional Studies as a Framework for the Design of Inhibitors and Activators
Miłosz Ruszkowski
2019-09-26
2023-08-25
2018/31/B/NZ3/03621
Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficiency in HD, using juvenile HD iPSC and fused brain organoids
2019-09-30
2023-09-29
2019/32/T/NZ3/00504
Discovering the molecular mechanisms of neurodegeneration in Ki91 knock-in mouse model during progression of spinocerebellar ataxia type 3
Kalina Wiatr
2019-10-01
2020-09-30
Etiuda 7
2019/03/X/NZ1/00027
Study of the secondary structure of the 5' terminal region of the Δ133p53 mRNA encoding the Δ133p53 and Δ160p53 p53 isoforms and determination of the properties of this region in the translation process
Paulina Żydowicz-Machtel
2019-10-10
2020-10-09
Miniatura 3
2018/30/E/NZ3/00624
Functional implications of brain-enriched circular RNAs
Monika Piwecka
2019-11-04
2023-11-03
2019/03/X/NZ4/00286
The effect of normal and mutated ataxin 3 on the immune system in the context of pathogenesis of cerebellum cerebellar ataxia type 3
Łukasz Przybył
2019-11-07
2020-11-06
2019/03/X/ST4/00197
Synthesis and characterization of pH-dependent probe conjugates and oligonucleotides forming tryplex structures
Michał Gładysz
2019/03/X/NZ2/00739
Point mutations of the SOD1 gene as targets for the allele-selective antisense strategy
Dorota Magner
2019-11-22
2020-11-21
2019/03/X/ST4/00828
Functionalization of nucleic acids by means of thermo-sensitive switches
Jolanta Brzezińska
2021-08-18
2018/31/F/NZ1/03891
Molecular basis for influenza virus activation by type II transmembrane serine proteases
Paweł Zmora
2020-01-15
2023-01-14
Beethoven Life 1
2019/33/B/ST4/01422
Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding predictions for a better understanding of their structure and function in mammalian cells
2023-02-24
Opus 17
2019/33/B/NZ1/02260
Defining roles of LINE-1 mRNA 5’ and 3’ ends in the retrotransposon biology
2020-03-02
2024-01-01
2020/01/0/NZ6/00152
TMPRSS2 – a potential new drug target and a determinant of COVID19 outcome
2020-06-05
2021-12-04
Fast Track COVID-19
2020/01/0/NZ1/00134
Validation of PDB models of potential drug design targets for SARS-CoV-2 coronavirus
2020/01/0/NZ6/00137
SARS-CoV-2 RNA, target for inhibition of virus replication
2020-06-15
2021-12-14
2019/35/N/NZ1/01954
Arc as a neuronal Gag. Exploring the viral properties and functions of a master regulator of synaptic plasticity
Julita Gumna
2022-08-18
Preludium 18
2019/35/B/ST4/03559
Exploring the sequence-structure relationship as a starting point for the design of DNA G-quadruplexes with a given topology - an integrative approach combining molecular simulations with experimental methods
2024-06-18
Opus 18
2019/35/D.NZ7/03637
Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular biology and medicine
2020-06-25
2023-12-24
Sonata 15
2019/35/N/NZ7/02777
Novel bispecific G-quadruplex conjugates as potential anticancer agents
Carolina Pereira Roxo
2020-07-06
2024-03-05
2019/35/D/NZ6/01479
The G-rich sequences in the influenza A virus genome – structural features and potential biological function in viral replication cycle
Marta Szabat
2020-09-01
2023-08-31
2020/36/C/NZ9/00221
Antibiotic resistance genes and integrons as indicators of biotic pollution and resistance load of Arctic ecosystems
Nicoletta Makowska
2020-09-02
Sonatina 4
2019/35/B/NZ3/03503
REGE-1 and RLE-1-dependent mRNA decay: The “R2-co” model of messenger RNA silencing
2021-03-18
2019/35/B/NZ1/03731
Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites
2024-09-29
2019/34/A/NZ3/00223
COLD-INDUCED TORPOR: Molecular mechanisms and manipulation for enhanced cellular preservation
2020-10-01
Maestro 11
2020/36/T/NZ2/00127
The use of genome editing systems in experimental therapy of polyglutamine diseases
Magdalena Dąbrowska
2021-09-30
Etiuda 8
2019/35/O/NZ1/03535
Allele-selective therapy for polyglutamine diseases with the use of RNA interference technology
2024-09-30
Preludium Bis 1
2019/35/B/NZ2/02658
Comprehensive analysis of the Schmidtea mediterranea transcriptome – identification of non-coding RNAs involved in cell lineage development during regeneration
2020-11-02
2024-11-01
2020/04/X/NZ3/00731
Experimental walidation of spinocerebellar ataxia type 3 pathogenesis markers that were identified by high throughput methods
Grzegorz Figura
2020-11-19
2021-11-18
Miniatura 4
2019/33/B/NZ5/02473
Deciphering the molecular causes and consequences of circular RNAs elevated expression levels in myotonic dystrophy type 1(DM1)
2020-11-27
2023-11-26
2020/04/X/NZ1/01959
Preliminary research on the chemical programming of fungi using Ramularia collo-cygni as a model
Dorota Jakubczyk
2020-12-12
2021-12-11
2020/04/X/NZ7/01461
Analysis of apro-regenerative and antioxidant properties of 4-N-furfurylcytosine in an animal model of Schmidtea mediterranea (Planaria)
Agnieszka Fedoruk-Wyszomirska
2022-04-14
2020/37/B/NZ3/03633
Non-coding RNAs at single-cell resolution in the pituitary gland and their role in the regulation of gene expression
2021-02-01
2025-01-31
Opus 19
2020/37/B/NZ5/03249
Application of small compounds in the epigenetic therapy of malignant brain gliomas
2024-01-31
2020/37/B/NZ1/03250
Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of enzymes with dual implications for drug design
2020/37/B/NZ7/02008
Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc oncogene transcription
2021-04-01
2025-03-31
2020/37/B/ST4/03182
Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectroscopy of nucleic acids
2020/39/B/NZ7/01519
Enzymes of the L-methionine biosynthetic pathway as novel molecular targets for antifungal chemotherapy
2021-07-08
2025-07-07
Opus 20
2020/39/B/NZ9/03336
Why cells become smaller to survive? Analysis of tobacco BY2 cells adapted to osmotic and salt stress in the search of key regulatory factors between energy management, molecular homeostasis and the size of the chronically stressed plant cells
2021-08-02
2025-08-01
2020/39/B/NZ5/01970
Identification of cancer-driver mutations in non-coding parts of protein-coding genes and long non-coding RNA genes
2021-08-24
2025-08-23
2021/05/X/NZ2/00063
Generation of a new cellular model based on the CRISPR-Cas technology (enChIP) to study mechanisms of DNA repair in microsatellite regions
Paweł Śledziński
2022-08-30
Miniatura 5
2020/39/B/NZ1/03054
Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small molecules towards inhibition of influenza virus replication
2021-09-01
2025-08-31
2020/39/B/NZ3/03020
Transcriptome-wide analysis of RNA structure in the cell and across cellular compartments, and identification of the impact of cellular factors on RNA structure in S. cerevisiae
2020/39/D/ST4/03177
Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRNA complexes
2024-08-31
Sonata 16
2020/39/D/NZ6/03267
Long noncoding RNA - new aim of anti-influenza therapy
Marta Soszyńska-Jóźwiak
2020/39/D/NZ2/03106
The effect of cancer somatic mutations in miRNA genes on the functioning of these genes and their potential role in cancer
2020/39/B/NZ3/01811
Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myotonic dystrophy type 2 (DM2)
2021-09-20
2025-09-19
2020/39/B/NZ9/00784
ABCG driven transport of phenylpropanoids in Medicago truncatula - a versatile but adapted scenario
2021/05/X/NZ1/00255
Production of the MtABCG46 protein in a heterologous system - preparation for structural analysis
Wanda Biała-Leonhard
2021-10-01
2022-09-30
2021/40/C/NZ4/00326
Psychedelics as Therapeutic Candidates in Neurodegenerative Disorders Treatment– a Study in Spinocerebellar Ataxia Type 3 Mouse Model
Urszula Kozłowska
Sonatina 5
2020/39/B/NZ2/03426
Molecular basis of glucosinolate modification and activation in the immunity of Brassicaceae species
2021-10-04
2025-10-03
2021/40/C/NZ3/00323
Aggregates of toxic polyglycine protein: in the spotlight. Understanding of formation and degradation processes
Magdalena Derbis
2024-10-03
2021/05/X/NZ7/00450
Optimization of bioprinting conditions to establish 3D hepatocellular carcinoma model as a screening platform for searching compounds with therapeutic potential
Dorota Gurda-Woźna
2021-11-02
2022-11-01
2021/05/X/NZ3/00684
Identification of proteins abolishing the interaction of the PABPC1 protein with the poly(A) tail of mRNA in early apoptosis
Damian Janecki
2021/05/X/NZ2/00795
Development of the new method of RNA 3' ends sequencing using Nanopore technology
Arkadiusz Kajdasz
2021-12-01
2022-11-30
2021/05/X/NZ1/00948
Effects of small-molecule ligands, selectively targeting the MALAT1 RNA triple helix, on the formation of the MALAT1/METTL16 complex
Agnieszka Ruszkowska
2019/34/H/NZ2/00584
Life at the limits: diversity, adaptation strategies and bioprospecting of microbes living in Arctic deep sea habitats
2021-12-10
2024-04-09
Projekty Programu Polsko-Norweskiej Współpracy Badawczej GRIEG
2021/05/X/NZ1/01778
Understanding the structural determinants of interactions between the PPC cassette of human ribonuclease Dicer and the RNA/ DNA molecules adopting G quadruplex structures
Kamil Szpotkowski
2022-12-13
2021/05/X/NZ7/01440
Preliminary studies on the development of a general strategy for residence time prolongation and selectivity enhancement of known, broad-spectrum activity inhibitors as exemplified for cycline-dependent kinases (CDK)
Michał Jakubczyk
2021/41/B/NZ9/03765
Airborne microbiome - characterization of microorganisms inhabiting particulate matter of urban areas and their impact on human health
2021-12-28
2025-12-27
Opus 21
2021/41/N/NZ2/03849
The cellular RNA interactome of the human Dicer helicase domain
Kinga Ciechanowska
2022-01-21
2024-01-20
Preludium 20
2021/41/N/NZ2/03047
Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system
2022-01-25
2023-01-24
2021/41/N/NZ1/03860
The use of artificial miRNAs in the therapy of Huntington's Disease
Anna Kotowska-Zimmer
2022-02-01
2023-01-31
2021/41/B/NZ2/03881
Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD
2026-01-31
2021/41/B/NZ3/03803
Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts
2021/41/B/NZ1/03819
Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates specific to conserved RNA motifs in Influenza A and SARS-CoV-2
2021/41/N/NZ1/04030
Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transporter
Konrad Pakuła
2022-02-07
2023-03-06
2021/41/N/NZ3/04060
Exploring Ty3 genomic RNA structure during retrotransposition in yeast
Angelika Andrzejewska-Romanowska
2025-02-06
2021/41/B/NZ2/03781
Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-quadruplex structures
2022-03-01
2026-02-28
2021/42/E/NZ2/00434
Functional or not functional? Studying positionally conserved vertebrate lncRNA orthologues at subcellular resolution
2022-06-01
2027-05-31
Sonata Bis 11
2021/41/B/NZ7/03910
Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent
2025-11-29
2021/43/O/NZ1/01590
Non-canonical pre-mRNA splicing participates in the editing of CNBP mutant allele in myotonic dystrophy type 2 (DM2)
2022-10-01
2026-09-30
Preludium Bis 3
2021/43/O/NZ2/01626
The role of transposable elements and epigenetic regulation of gene expression in Medicago truncatula root nodules development
2021/43/B/NZ2/01615
Searching for new therapeutic targets in polyglutamine diseases
2022-07-01
2026-06-30
Opus 22
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